Pharmacokinetic mapping for lesion classification in dynamic breast MRI
نویسندگان
چکیده
منابع مشابه
Pharmacokinetic mapping for lesion classification in dynamic breast MRI.
PURPOSE To prospectively investigate whether a rapid dynamic MRI protocol, in conjunction with pharmacokinetic modeling, could provide diagnostically useful information for discriminating biopsy-proven benign lesions from malignancies. MATERIALS AND METHODS Patients referred to breast biopsy based on suspicious screening findings were eligible. After anatomic imaging, patients were scanned us...
متن کاملIntegration of DCE-MRI and DW-MRI Quantitative Parameters for Breast Lesion Classification
OBJECTIVE The purpose of our study was to evaluate the diagnostic value of an imaging protocol combining dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted MRI (DW-MRI) in patients with suspicious breast lesions. MATERIALS AND METHODS A total of 31 breast lesions (15 malignant and 16 benign proved by histological examination) in 26 female patients were included in this study. For ...
متن کاملQuantifying heterogeneity of lesion uptake in dynamic contrast enhanced MRI for breast cancer diagnosis
The current study investigates whether texture features extracted from lesion kinetics feature maps can be used for breast cancer diagnosis. Fifty five women with 57 breast lesions (27 benign, 30 malignant) were subjected to dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) on 1.5T system. A linear-slope model was fitted pixel-wise to a representative lesion slice time series and f...
متن کاملCharacterization of breast lesion morphology with delayed 3DSSMT: an adjunct to dynamic breast MRI.
The purpose of the study was to determine the sensitivity and specificity of various morphologic criteria in distinguishing malignant from benign breast lesions using a new sequence (3DSSMT) performed immediately after dynamic breast MRI. 3DSSMT combines a water-selective spectral-spatial excitation and an on-resonance magnetization transfer pulse with three-dimensional spoiled gradient-echo im...
متن کاملThe use of error-category mapping in pharmacokinetic model analysis of dynamic contrast-enhanced MRI data
This study introduces the use of 'error-category mapping' in the interpretation of pharmacokinetic (PK) model parameter results derived from dynamic contrast-enhanced (DCE-) MRI data. Eleven patients with metastatic renal cell carcinoma were enrolled in a multiparametric study of the treatment effects of bevacizumab. For the purposes of the present analysis, DCE-MRI data from two identical pre-...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2010
ISSN: 1053-1807,1522-2586
DOI: 10.1002/jmri.22179